Dr. Sara Gottfried: How to Optimize Female Hormone Health for Vitality & Longevity | Huberman Lab

My guest is Sara Gottfried, M.D., a Harvard-trained, board-certified gynecologist and clinical assistant professor of integrative medicine & nutritional sciences at Thomas Jefferson University. Dr. Gottfried specializes in hormone health, vitality and longevity using precision/personalized approaches. We discuss female hormone health, puberty, perimenopause, and menopause, hormone testing, the microbiome, stress related hormone challenges, their causes, and various treatments. We also discuss fertility, birth control and tools for improving microbiome health, treating PCOS, insulin management, and the best nutrition, supplementation, and exercise programs for women. While the episode focuses mainly on female hormones, males will also benefit from our discussion because it includes actionable tools suggested for managing stress, bolstering the gut microbiome, and immunity—all of which stand to improve overall health, vitality and longevity in males and females.



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Dr. Sara Gottfried

Website: https://www.saragottfriedmd.com

Academic Profile: https://bit.ly/3wI7vBz

Medical Practice: https://bit.ly/3jcopoE

Twitter: https://twitter.com/drgottfried

Instagram: https://www.instagram.com/saragottfriedmd

TikTok: https://www.tiktok.com/@saragottfriedmd

YouTube https://www.youtube.com/drgottfried

Facebook https://www.facebook.com/DrGottfried

LinkedIn: https://www.linkedin.com/in/drgottfried

The Critical Link Between Healthy Hormones and Your Relationships: https://bit.ly/40aKXqx



Articles

Women: Diet, Cardiometabolic Health, and Functional Medicine: https://bit.ly/3WPsjl0

Continuous glucose monitoring metrics for earlier identification of pre-diabetes: protocol for a systematic review and meta-analysis: https://bit.ly/3HDX9cc

Brief structured respiration practices enhance mood and reduce physiological arousal: https://bit.ly/3wEvGRf



Books

The Hormone Cure: https://amzn.to/3RwnhdV

Women Food and Hormones: https://amzn.to/3uLAM0y



Other Resources

Genova Diagnostics Metabolomix Test: https://bit.ly/3HDfPc3

Genova Diagnostics NutrEval: https://bit.ly/3JlHmQB

SpectraCell Laboratories Micronutrient Test: https://bit.ly/3WMJmnS

Omega Quant Tests: https://bit.ly/3kUiiFT

Cleveland HeartLab® Cardiometabolic Disease: https://bit.ly/3Jl4jTX

Genova Diagnostics Stool Test: https://bit.ly/3JqaVR8

Thorne Gut Health Test: https://thor.ne/y9GEp

"Men are not the patriarchy," Pat McCabe: https://bit.ly/3HFU3nW



Timestamps

00:00:00 Dr. Sara Gottfried

00:03:51 ROKA, Thesis, LMNT, Momentous

00:07:50 Women, Family History, Heredity & Environment

00:11:00 Puberty, Stress, Menstrual Cycles, Intrauterine Devices (IUDs)

00:17:26 Tool: Sex Hormones, Microbiome, Estrobolome & Disease; Biomarker Testing

00:25:11 Nutritional Testing; Vegetables, Microbiome & Disease

00:31:13 AG1 (Athletic Greens)

00:32:22 Microbiome, Prebiotics & Probiotics, Inflammation

00:36:08 Microbiome Testing, Magnesium, Constipation & Thyroid

00:42:25 Female Colonoscopy; Network Effect & Modern Medicine, Stress Factors

00:45:13 Constipation, Stress & Trauma, Autonomic Balance

00:55:35 Constipation Relief, Stress, Breathwork & Meditation

01:02:58 Systemic & Societal Stress Unique to Females

01:08:19 InsideTracker

01:09:23 Testing & Future Behavior

01:11:55 Polycystic Ovary Syndrome (PCOS) & Cardiometabolic Disease; Stress

01:22:57 PCOS, Insulin, Glucose Monitoring and Management; Data Access

01:29:48 Behaviors for Vitality; Exercise & Body Phenotype; Cortisol

01:36:40 Cortisol Supplements: Ashwagandha, Rhodiola, Fish Oil, Phosphatidylserine

01:42:36 Cortisol, Anxiety & Immune System; Adrenal Function, Resilience

01:48:07 Tool: Omega-3 Fatty Acids, Inflammation, Specialized Pro-Resolving Mediators

01:54:20 Oral Contraceptives, Benefits & Risks; Ovarian Cancer; Testosterone

02:06:50 Fertility, Follicular & Anti-Mullerian Hormone (AMH) Assessments

02:10:29 Menopause & Hormone Replacement Therapy; Women’s Health Initiative

02:15:30 Perimenopause, Cerebral Hypometabolism, Metabolism & Estrogen

02:21:49 Intermittent Fasting, Ketogenic Diet, Metabolic Flexibility

02:23:29 Stool Testing

02:25:32 Coronary Artery Calcium (CAC) Test, ACE Score & Disease

02:31:56 Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Social Media, Neural Network Newsletter, Momentous



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